Reductive amination with zinc powder in aqueous media

نویسندگان

  • Giovanni B Giovenzana
  • Daniela Imperio
  • Andrea Penoni
  • Giovanni Palmisano
چکیده

Zinc powder in aqueous alkaline media was employed to perform reductive amination of aldehydes with primary amines. The corresponding secondary amines were obtained in good yields along with minor amounts of hydrodimerization byproducts. The protocol is a green alternative to the use of complex hydrides in chlorinated or highly flammable solvents.

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عنوان ژورنال:

دوره 7  شماره 

صفحات  -

تاریخ انتشار 2011